The Potential of Nanopore Sequencing to Profile Lymphoproliferative Malignancies and Other Neoplasms

Nanopore sequencing has become the talk of the town—well, at least around sequencing labs. It has emerged as a serious competitor to the solid second-generation sequencing-by-synthesis techniques offered by Illumina or Ion Torrent. In brief, this method uses an ionic current passing through a channel with the DNA strand and the resulting flow profile to determine the base composition in real-time.